The Sisters with Lupus Research Project - University of Minnesota - Do you and another family member have Lupus If so, you can be involved in the search for the cause. We are looking nationwide for multiple family members with systemic lupus erythematosus (SLE or lupus). We hope to discover why certain women get lupus by identifying inherited genetic factors.

Resource file on Cutaneous Systemic Lupus Erythmatosus

Renal involvement in systemic lupus erythematosus is a common disease manifestation and a strong predictor of poor outcome.

This site is an illustration of discoid lupus erythematosus.

Lupus patients often have a concurrent fibromyalgia syndrome. Wallace reported a 22% prevalence in 464 lupus patients, Middleton reported a 22% prevalence of fibromyalgia meeting the ACR criteria with another 23% having probable fibromyalgia, and Morand reported a 25% prevalence of fibromyalgia in a cohort of 87 lupus patients

This site is an illustration of discoid lupus erythematosus.

Researchers at the Arizona Arthritis Center are coordinating two major studies that show promise in helping alleviate or prevent symptoms that affect patients with systematic lupus. "One of the studies is on the effects of the hormone DHEA (dehdroepiandrosterone) on patients with lupus and the other is on a new immunological therapy to treat kidney inflammation that is caused by lupus, said Mark Iannini, M.D., principal investigator on both studies.

UniGene

In a study reported in the Proceedings of the National Academy of Sciences (April 29, 1997, Vol. 94), Mozes's team synthesized two protein fragments that effectively immunized mice against lupus. The protein fragments were designed to mimic sections of the abnormal antibodies produced in lupus. Although their precise mechanism has not been fully clarified, studies indicate that they prevent the initiation of the autoimmune response. Where the disease already exists, preliminary results in mice suggest that

A group of scientists from the Oklahoma Medical Research Foundation report today in the The Journal of Clinical Investigation that systemic lupus erythematosus (lupus) may be caused by a common virus.

Studies on mice with a disease similar to systemic lupus erythematosus, a devastating autoimmune disease that causes chronic inflammation and severe kidney disease, point to a novel therapeutic approach to treating this disease in humans, report scientists from The Rockefeller University in the Feb. 13 issue of the journal Science.