- Last Updated: May 29th, 2002 The College of Nurses of Ontario (CNO) is the governing body for the 140, 000 registered nurses (RNs) and registered practical nurses (RPNs) in Ontario, Canada. We regulate nursing to protect the public interest. The College sets requirements to enter the profession, establishes and enforces standards of nursing practice, and assures the quality of practice of the ...www.cno.org