- Healthcare professionals and scientists have carefully prepared this ALtruis Biomedical Network-affiliated site, intended for informational purposes only. Partners: Physiology | Female Characteristics | Hormone Replacement | The Pill Natural Estrogens All naturally occurring estrogens (estrone, estradiol, and estriol) are C18 steroids secreted by the theca interna and granulosa cells of the ...www.e-estrogens.com