Upper St John River Valley Access to the Region Access to the Madawaska-Victoria Region is through a main central highway: the Trans-Canada Highway and four secondary highways. In New Brunswick Trans-Canada Highway (2) Secondary Routes (17, 105, 108, 385). From Quebec Highway 185 South (Exit 499), Secondary Routes 289 (Exit 488) From the United States Perth Andover (route 190) Gillepsie (route ...