Take Hwy. 340 north to McGregor, IA Clayton and Guttenberg, Iowa Take Hwys. 52 and 386 south to N. Buena Vista, IA or ride the ferry east to Cassville, WI Antiques not yet available Guttenberg is located on U.S. Highway 52, 40 miles north of Dubuque. With the broad river to the East and the high bluffs to the West, it combines the scenic beauty of both river and highland as no other city on the ...