Conjunctivitis, Giant Papillary - Giant papillary conjunctivitis (GPC) is a common complication of contact lens wear, first described by Spring in 1974 in association with contact-lens use. Papillary changes can occur in the ocular tarsal palpebral conjunctivae as part of a Gel-Coombs type 1 (immunoglobulin [Ig] E-mediated) hypersensitivity reaction.Prior to popularization of hydrogel (soft) ...

Giant Papillary Conjunctivitis Signs and Symptoms Giant papillary conjunctivitis (GPC) is a common condition frequently seen in soft contact lens patients, patients with exposed suture knots, and patients with prostheses. Patients with asthma, hay fever or animal allergies may be at greater risk. The etiology of GPC may be immunological, where contact lens deposits act as allergens. Initial ...

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